报告时间：2026年7月9日（星期四）14:30-15:30
报告地点：昇华楼616会议室
报 告 人：René Michael Koenigs 教授
工作单位：拜罗伊特大学
举办单位：化学与化工学院，高值催化转化与反应工程安徽省重点实验室，安徽省柔性智能材料创制与应用工程研究中心
报告简介：
Visible-light activation has fundamentally changed the way reactive intermediates are generated and controlled in synthetic chemistry. Beyond providing a sustainable source of energy, light offers direct access to electronically excited states whose reactivity differs fundamentally from that of their thermal counterparts. The ability to selectively access reactive intermediates with distinct spin multiplicities has opened new opportunities for reaction discovery, enabling selective bond constructions that remain inaccessible by conventional catalytic strategies.
This lecture highlights the development of photochemical strategies that exploit the unique reactivity of open-shell intermediates across different spin manifolds. Beginning with doublet radical chemistry, visible-light activation has enabled catalyst-free and photocatalyst-assisted C–H functionalization reactions, late-stage diversification of complex molecules, and the selective generation of carbon-centered radicals. Extending these concepts to carbene chemistry, direct photoexcitation of diazo compounds has provided access to free singlet and triplet carbenes, revealing how subtle changes in electronic structure govern reaction selectivity and permit unconventional carbene-transfer reactions, strain-release processes, and radical cascades that complement classical transition-metal catalysis. Most recently, these concepts have been translated to nitrene chemistry, where the controlled generation of triplet nitrenes has enabled selective intermolecular amination reactions, cycloadditions, and strain-release transformations, demonstrating how spin-state control can unlock entirely new synthetic disconnections.
Together, these examples illustrate how a mechanistic understanding of electronic structure and spin-state reactivity can serve as a guiding principle for reaction design. Rather than considering radicals, carbenes, and nitrenes as distinct classes of reactive intermediates, they emerge as part of a unified conceptual framework in which light enables precise control over molecular reactivity and selectivity.
报告人简介：
René Michael Koenigs（雷内 麦克 柯尼希斯）教授，博士毕业于德国亚琛工业大学。2015年加入亚琛工业大学有机化学研究所，任助理教授，2022年-至今为教授。2025年4月加入拜罗伊特大学，任教授，有机化学方向主任。主要研究方向为卡宾和氮宾转移反应及其应用。Koenigs教授2023荣获澳大利亚研究委员会未来研究员计划（Australian Research Council Future Fellowship）；2021年获得亚琛工业大学FAMOS卓越领导力奖（RWTH Aachen FAMOS award for excellence in leadership）。相关研究成果在Science、Nature Commun、Angew. Chem. Int. Ed.等期刊发表。
